Dorsal horn NK1-expressing neurons control windup of downstream trigeminal nociceptive neurons
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چکیده
منابع مشابه
Dorsal horn NK1-expressing neurons control windup of downstream trigeminal nociceptive neurons.
Windup is a progressive, frequency-dependent increase in the excitability of trigeminal and spinal dorsal horn wide dynamic range (WDR) nociceptive neurons to repetitive stimulation of primary afferent nociceptive C-fibers. Superficial dorsal horn neurokinin 1 receptor (NK1R)-expressing neurons were recently shown to regulate sensitization of WDR nociceptive neurons through activation of a defi...
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ژورنال
عنوان ژورنال: Pain
سال: 2008
ISSN: 0304-3959
DOI: 10.1016/j.pain.2007.09.017